Two novel models evaluating the determinants of resting metabolic rate in Indian children

Background: Resting metabolic rate (RMR) quantifies the minimal energy required to sustain vital body functions and is a crucial component of childhood development. Mean RMR per unit mass (RMR/BM) has very accurately been modelled in references for Caucasian adolescents.Objectives: Here we address extent which such model can be adapted explain RMR/BM Indian children.Subjects Methods: The multicenter study (MCS) cross-sectional dataset on 495 children (235 girls 260 boys) aged 9 19 years with anthropometric, composition, measurements. RMR-ultrasonography (RMR-USG) consists anthropometric data, RMR, liver kidney volume measured through ultrasonography nine boys 6 8 years.Results: mean significantly lower compared their counterparts, except age group 9–13 years. We present two novel phenomenological models that describe stratified by adolescents. first modified Wang relative masses four major organs are assumed uniformly lowered children. Theoretical predictions size not borne out pilot validation study; however, found lower. second demonstrates changes composition alone also data.Conclusion: A differences used estimate children; understanding mechanistic basis variation remains an open problem.